Genomics and Personalised Medicine

Year 0, Semester 1 Elective Medical Science

Back
Code CLS6012-B
Credits 20
Graduate Attributes
Syllabus The module will cover the underlying theories of genes, genomes and epigenetics relevant to human disease. It will then survey the technologies that detect and analyse these changes, including genomics, proteomics, metabolomics, whole genome and RNA sequencing in research and health care settings. These topics will be related to the diagnosis, monitoring and treatment of human disease. The role of genomics and related technologies will be further explored in common and rare inherited diseases, cancer, as well as infectious diseases. A specific focus will be on the development of novel treatment strategies such as gene editing and the stratification of patients using genome-based personalized medicine. The module will also cover the ethical and social implications of applied genomics as well as its commercial potential.
Lecture 12 
Workshop 10 
Private Study 178 

Unit Learning Outcomes

  • 1 Demonstrate a systematic understanding of genes, genomes and epigenetics relevant to human health and disease and have an appreciation of the validity and limits of this knowledge.
  • 2 Critically assess different methodologies related to genomics and personalised medicine.
  • 3 Apply the principles of genomics and related research fields to the diagnosis and treatment of disease.
  • 4 Apply knowledge and understanding to allow effective critical appraisal of research literature.
  • 5 Critically assess the ethical, societal, and economic implications of genomics and personalised medicine.

Course Learning Outcomes

  • 22 Critically analyse and interpret current and future trends and developments in science and healthcare provision in a socioeconomic and global context.
  • 23 Understand and demonstrate coherent and detailed subject knowledge informed by recent research/scholarship in medical & clinical sciences.
  • 26 Critically analyse and present findings from relevant literature and experimental data using independent learning skills with an appreciation of the uncertainty ambiguity and limits of knowledge.

Assessment Breakdown

Genomics and Personalized Medicine aims to develop knowledge and understanding of advanced concepts related to genomics and personalized medicine, including an understanding of the underlying science and technologies employed in the field. It further aims to apply these concepts in a medical, clinical and social context, including their relevance to the identification of biomarkers and the application of precision medicine. The module also aims to provide an understanding and critical appraisal of novel therapies and diagnostic advancements in personalized medicine, including strategies to stratify and manage patients. It will also promote enquiries into the ethical and social implications of applied genomics and related technologies and to understand their commercial applications.